https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42575 Thu 25 Aug 2022 14:21:14 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20442 Sat 24 Mar 2018 08:06:54 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:21235 N = 28 854) and CC-free (N = 86 562) patients had mean age 61.9 years; 66.7% were female. One-year CRCancer prevalence was 2.7% and 1.7%, and BCN prevalence was 24.8% and 11.9% for CC and CC-free patients, respectively. Adjusted IRRs between CC and CC-free patients were 1.59 [95% confidence interval (CI): 1.43-1.78] and 2.60 [95% CI: 1.51-2.70] for CRCancer and BCN, respectively. Patients with severe and very severe CC had significantly greater incidence of CRCancer and BCN. At ≥2 and ≥5 years of observation, CRCancer and BCN incidence remained consistently and significantly higher for CC patients. Conclusions Patients with chronic constipation are associated with significantly higher prevalence and incidence of colorectal cancer and benign colorectal neoplasm than matched chronic constipation-free patients. These risks increase with the severity of chronic constipation.]]> Sat 24 Mar 2018 07:53:01 AEDT ]]>